Drug Development
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Two Women-Led Companies Developing mRNA Drugs to Fight Primary Ciliary Dyskinesia
A rare genetic respiratory disease affecting the tiny structures in the lungs that filter air is the target of promising new gene therapies delivered directly to the lungs via an inhaler.
Retina’s Layers, Eye’s Blood Vessels May Distinguish NMOSD From MS
Cholinesterase Inhibitors Found to Slow Long-term Cognitive Decline
Autophagy-targeting Compound Fails to Reduce Heparan Sulfate in Mice
Vamorolone Trial for DMD Finishes Pivotal First Part, Results Awaited
Inflammatory Immune Cells Found in Active, But Not Chronic, Brain Lesions
NfL Promising Biomarker for Predicting Tecfidera Response
Vitamin D Binding Protein a Potential Biomarker in MS
Lower blood levels of vitamin D binding protein, known as VDBP, were observed in newly diagnosed multiple sclerosis (MS) patients in a new study — findings that suggest the protein could potentially act as a biomarker for the neurodegenerative disease.
“The present study revealed an independent association between lower … levels of VDBP and the risk of MS,” the researchers wrote. However, the team said further studies are needed to confirm their findings.
The study, “Reduction in circulating v
“The present study revealed an independent association between lower … levels of VDBP and the risk of MS,” the researchers wrote. However, the team said further studies are needed to confirm their findings.
The study, “Reduction in circulating v
Combining Different Tests Gives Clearer View of Patient Life Quality
The combined use of generic and disease-specific health-related quality of life (HRQoL) measures gives a clearer representation of the effects of multiple sclerosis on patients’ quality of life and enables a more accurate comparison across countries, a study has found.
“The effects of MS on HRQOL in real-world patients may be underestimated,” the researchers wrote.
“The combined use of both generic and disease-specific HRQOL instruments as outcome measures in clinical trials and observational
“The effects of MS on HRQOL in real-world patients may be underestimated,” the researchers wrote.
“The combined use of both generic and disease-specific HRQOL instruments as outcome measures in clinical trials and observational
Mindfulness Helps to Reduce Depression, Fatigue in MS Patients
Switching From Gilenya to Lemtrada May Not Be Optimal Choice, Study Says
Survey: COVID-19 Concerns Affected MS Management
Nerve Cell Loss in Retina Found to be Worse in Patients on Interferon-beta
TH17-suppressing Pregnancy Proteins May Be MS Therapeutic Target
According to the scientists, this research could be used to develop new therapies for maintaining pregnancy and treating various autoimmune diseases.
2021 Innovation Challenge Finalists Announced
PPMS Patients ‘Drove’ Slowing in Brain Atrophy Seen With Ibudilast
Obesity, High BMI Linked to Greater MS Risk, Autoimmune Activity
Mentally Overestimating Motor Tasks May Cause Cognitive Fatigue in MS
People with multiple sclerosis (MS) tend to mentally overestimate the time required to complete a short walking activity, causing cognitive fatigue that may affect their quality of life, a study reports.
Stem Cell Therapy Shows 2-year Benefit for Progressive MS Patients in Phase 1 Trial
Tecfidera Found in Breast Milk But Levels Appear Safe, Case Study Reports
Disease Progression Differs More Across MS Type Than Sex of Patients, Study Finds